Boswellin

One of the active constituents in boswellin is Boswellic Acid, a pyrazoline derivative which has been shown to exhibiti anti-inflammatory activity and has proven very effective in supporting healthy joints. Boswellic acids (BA) are believed to suppress the proliferating tissue found in the inflammed areas and also prevent the breakdown of connective tissue. The mechanism is similar to the action of non steroidal groups of anti-arthritic drugs but with no side effects, gastric irritation and ulcerogenic activity.

Research conducted in India found that an extract of Boswellia was more beneficial, less toxic, and more potent than the standard drug of choice for rheumatic disorders, Ketoprofen (benzoyl hydrotropic acid). Ketoprofen is preferred over other anti-inflammatories such as indomethacin, phenylbutazone or acetylsalicylic acid.

Many studies conducted since the original study has confirmed that Boswellia serrata has potent anti-inflammatory and anti-arthritic activity. Additionally, Boswellia was found to improve blood supply to the joints and restore integrity of vessels weakened by spasm. Boswellia has been successfully used to treat Bursitis, Osteoarthritis and Rheumatoid arthritis. In a double blind placebo controlled study, 12 patients with osteoarthritis were given a herbal formula consisting of Boswellin, Aswagandha, and turmeric or placebo for three months. The patients were evaluated every two weeks. After a fifteen day washout period, the treatment was reversed with the placebo patients getting the drug and vice versa. The results were evaluated over a three month period. The patients receiving the herbal formula showed a significant drop in severeity of pain and disability score.